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Item specifics

Condition
New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ...
PublishedOn
2012-03-14
Title
Nifidipine Matrix Tablet
ISBN
9783846589915
Publication Year
2012
Type
Textbook
Format
Paperback
Language
English
Publication Name
Nifidipine Matrix Tablet
Item Height
229mm
Author
Sohel Rana, Dewan Taslima Akhter, Riaz Uddin
Publisher
LAP
Item Width
152mm
Subject
Medicine
Item Weight
227g
Number of Pages
148 Pages

About this product

Product Information

The purpose of the present work was to design & evaluate sustained release tablets of Nifedipine, employing hydrophilic polymer to improve dissolution rates of the drug. METHOCEL K15MCR & METHOCEL K100LVCR were used in tablets prepared by direct compression. The formulated tablets were physicochemically characterized & results were found in acceptable limits. Poor aqueous solubility of Nifedipine leads to variable dissolution rates. The main effect & interaction terms were quantitatively evaluated using mathematical models. Dissolution data were fitted to zero order, first order, Higuchi's, Korsmeyer-Peppas & Hixson-Crowell release kinetics to evaluate kinetic data. The drug release data fit well to the Higuchi expression, but a close relationship was also noted with zero order kinetics. Korsmeyer's plot indicated that the drug release mechanism from the matrix tablet was to be found Fickian mechanism. Regulated drug release study indicate that the matrix tablets of Nifedipine prepared using above polymers can successfully be employed as twice-a-day oral controlled release dosage form.

Product Identifiers

Publisher
LAP
ISBN-13
9783846589915
eBay Product ID (ePID)
114006083

Product Key Features

Author
Sohel Rana, Dewan Taslima Akhter, Riaz Uddin
Publication Name
Nifidipine Matrix Tablet
Format
Paperback
Language
English
Subject
Medicine
Publication Year
2012
Type
Textbook
Number of Pages
148 Pages

Dimensions

Item Height
229mm
Item Width
152mm
Item Weight
227g

Additional Product Features

Title_Author
Sohel Rana, Riaz Uddin, Dewan Taslima Akhter
Country/Region of Manufacture
Germany

Item description from the seller

Business seller information

WRAP Ltd.
Mubin Ahmed
Unit 4
119 Loverock Road
Reading
Berkshire
RG30 1DZ
United Kingdom
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:enohP60358080080
:liamEmoc.aidemtumahab@yabe
Value added tax number:
  • GB 724498118
Trade registration number:
  • 03800600
I certify that all my selling activities will comply with all EU laws and regulations.
CRN Number:
  • 03800600
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