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Reprogrammatio
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eBay item number:296174134233
Item specifics
- Condition
- PublishedOn
- 2010-12-17
- Title
- Reprogrammation epigenetique des cellules musculaires lisses aor
- ISBN
- 9786131547119
- Publication Year
- 2018
- Type
- Textbook
- Format
- Paperback
- Language
- French
- Book Title
- Reprogrammation Pig N Tique Des Cellules Musculaires Lisses Aortiques
- Item Height
- 229mm
- Publisher
- Omniscriptum
- Topic
- Literature, Biology
- Item Width
- 152mm
- Item Weight
- 313g
- Number of Pages
- 208 Pages
About this product
Product Information
L'an vrysme de l'aorte thoracique (TAA) est une dilatation chronique de la paroi aortique caract ris e par une d gradation de la matrice extracellulaire et la rar faction en cellules musculaires lisses (CML). Ces manifestations sont communes tous les types de TAA (g n tiques ou non g n tiques). Notre hypoth se est qu'au monomorphisme tissulaire s'ajoute un ensemble de perturbations mol culaires communes. Ainsi, une d r gulation de la voie TGF- 1/Smad a t suspect e. L'activation de Smad2 se r v le tre un v nement commun tous les TAA. Cette tude a d bouch sur la mise en vidence d'une r gulation pig n tique ma trisant l'expression de Smad2 et lui conf re des propri t s uniques: autonomisation, h ritabilit , sp cificit cellulaire. Ce m canisme pig n tique module l'activation du g ne SMAD2 par modification du code histone et recrutement de facteurs nucl aires. Ce processus entra ne une modification du profil d'expression de la CML et conduit l' tablissement d'un ph notype protecteur anti-apoptotique. Cette tude permet une meilleure compr hension de l'impact de la signalisation Smad2 et de l'importance des processus compensatoires dans les TAA.
Product Identifiers
Publisher
Omniscriptum
ISBN-13
9786131547119
eBay Product ID (ePID)
205482905
Product Key Features
Book Title
Reprogrammation Pig N Tique Des Cellules Musculaires Lisses Aortiques
Format
Paperback
Language
French
Topic
Literature, Biology
Publication Year
2018
Type
Textbook
Number of Pages
208 Pages
Dimensions
Item Height
229mm
Item Width
152mm
Item Weight
313g
Additional Product Features
Series Title
Omn.Univ.Europ.
Item description from the seller
Business seller information
WRAP Ltd.
Mubin Ahmed
Unit 4
119 Loverock Road
Reading
Berkshire
RG30 1DZ
United Kingdom
Value added tax number:
- GB 724498118
Trade registration number:
- 03800600
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eBay item number:296174134233
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