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Formulation and Evaluation of Sublingual Tablet of Rabeprazole Sodium <|
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Located in: South East, United Kingdom
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eBay item number:305376733475
Item specifics
- Condition
- PublishedOn
- 2014-05-06
- Title
- Formulation and Evaluation of Sublingual Tablet of Rabeprazole S
- ISBN
- 9783659540189
- Publication Year
- 2014
- Type
- Textbook
- Format
- Paperback
- Language
- English
- Publication Name
- Formulation and Evaluation of Sublingual Tablet of Rabeprazole Sodium
- Item Height
- 229mm
- Publisher
- LAP
- Item Width
- 152mm
- Subject
- Medicine
- Item Weight
- 209g
- Number of Pages
- 136 Pages
About this product
Product Information
The present work introduces a new tablet system for sublingual administration in which the tablet is based on interactive mixtures of components, consisting of carrier particles partially covered by fine dry particles of the drug, in this case Rabeprazole sodium. In the interests of increasing retention of the drug at the site of absorption in the oral cavity, a bioadhesive component was also added to the carrier particles. With this approach, it is possible to obtain rapid dissolution in combination with bioadhesive retention of the drug in the oral cavity. Rabeprazole sodium is an anti ulcer drug having oral bioavailability 52% due to hepatic first pass metabolism. This work aims to avoid degradation of drug in acidic environment of stomach. In this study, Rabeprazole sodium sublingual tablets were prepared by direct compression method using different bioadhesive polymers such as HPMC K4M and chitosan and sodium starch glycolate as a superdisintegrant. The effect of different concentration of polymers and superdisintegrating agents was measured by applying Box-Behnken design.
Product Identifiers
Publisher
LAP
ISBN-13
9783659540189
eBay Product ID (ePID)
229421220
Product Key Features
Publication Name
Formulation and Evaluation of Sublingual Tablet of Rabeprazole Sodium
Format
Paperback
Language
English
Subject
Medicine
Publication Year
2014
Type
Textbook
Number of Pages
136 Pages
Dimensions
Item Height
229mm
Item Width
152mm
Item Weight
209g
Additional Product Features
Item description from the seller
Business seller information
WRAP Ltd.
Mubin Ahmed
Unit 4
119 Loverock Road
Reading
Berkshire
RG30 1DZ
United Kingdom
Value added tax number:
- GB 724498118
Trade registration number:
- 03800600
I certify that all my selling activities will comply with all EU laws and regulations.
CRN Number:
- 03800600
Seller assumes all responsibility for this listing.
eBay item number:305376733475
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