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B Cell Receptor Signaling - 9783319261317

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Item specifics

Condition
New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ...
Book Title
B Cell Receptor Signaling
ISBN
9783319261317
Publication Year
2016
Type
Textbook
Format
Hardcover
Language
English
Publication Name
B Cell Receptor Signaling
Item Height
235mm
Author
Jurgen Wienands, Tomohiro Kurosaki
Publisher
Springer International Publishing A&G
Item Width
155mm
Subject
Medicine, Biology
Item Weight
4912g
Number of Pages
231 Pages

About this product

Product Information

This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton's Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.

Product Identifiers

Publisher
Springer International Publishing A&G
ISBN-13
9783319261317
eBay Product ID (ePID)
223819891

Product Key Features

Author
Jurgen Wienands, Tomohiro Kurosaki
Publication Name
B Cell Receptor Signaling
Format
Hardcover
Language
English
Subject
Medicine, Biology
Publication Year
2016
Type
Textbook
Number of Pages
231 Pages

Dimensions

Item Height
235mm
Item Width
155mm
Volume
393
Item Weight
4912g

Additional Product Features

Series Title
Current Topics in Microbiology and Immunology
Country/Region of Manufacture
Switzerland
Editor
Jurgen Wienands, Tomohiro Kurosaki

Item description from the seller

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BOOKS ETC LIMITED
Andy Smith
Books Etc, Unit 4
Eastern Road
Aldershot
Hampshire
GU12 4YD
United Kingdom
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Value added tax number:
  • GB 976952259
Trade registration number:
  • 06687355
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I certify that all my selling activities will comply with all EU laws and regulations.
CRN Number:
  • 06687355
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