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Leishmaniasis: The Current Status and New Strategies for Control - 9781461288626

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Item specifics

Condition
New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ...
Book Title
Leishmaniasis: The Current Status and New Strategies for Control
ISBN
9781461288626
Publication Year
2013
Type
Textbook
Format
Paperback
Language
English
Publication Name
Leishmaniasis: The Current Status and New Strategies for Control: Proceedings of the NATO Advanced Study Institute, Zakynthos (Greece), 1987
Item Height
254mm
Author
D.T. Hart
Publisher
Springer-Verlag New York Inc.
Item Width
178mm
Subject
Medicine, Biology
Item Weight
1974g
Number of Pages
1041 Pages

About this product

Product Information

V Pentostam, an uncharacterized complex of Sb and carbohydrate derived from gluconic acid, is concentrated by Leishmania amastigotes via protein binding. Biochemical consequences of the interaction of amastigotes with Pentostam are inhibition of parasite bioenergetics and inhibition of ATP synthesis. REFERENCES 1. J.C. Mottram and G.H. Coombs. Enzyme activities of amastigotes and promastigotes and their inhibition by antimonials and arsenicqls. Exper. Parasitol. 59:151 (1985). 125 2. S.L. Croft, K.D. Neame and C.A. Homewood. Accumulation of [ Sb] sodium stibogluconate by Leishmania mexicana amazonensis and Leishmania donovani in vitro. Compo Biochem. Physiol. 68c:95 (1981). 3. J.D. Berman, J.V. Gallalee, and B.D. Hansen. Leishmania mexicana: uptake of sodium stibogluconate (Pentostam) and pentamidine by parasite and macrophages. Exper. Parasitol. 64:127 (1987). 4. J.D. Berman, D. Waddell and B.D. Hanson. Biochemical meChanisms of the antileishmanial activity of sodium stibogluconate. Antimicrobial Agents Chemotherapy. 27:916 (1985). 5. J.D. Berman, J.V. Gallalee, and J.M. Best. Sodium stibogluconate (Pentostam) inhibition of glucose catabolism via the glycolytic pathway, and fatty acid B-oxidation in Leishmania mexicana amastigotes. Biochem. Pharmacol. 36:197 (1987). 6. D.T. Hart and G.H. Coombs. Leishmania mexicana: Energy metabolism of amastigotes and promastigotes. Exper. Parasitol. 54:397 (1982). 478 EFFECTS OF SINEFUNGIN ON CELLULAR AND BIOCHEMICAL EVENTS IN PROMASTIGOTES OF LEISHMANIA d. donovani Fran~oise Lawrence, and MaIka Robert-Cero Institut de Chimie des Substances Naturelles C.N.R.S.

Product Identifiers

Publisher
Springer-Verlag New York Inc.
ISBN-13
9781461288626
eBay Product ID (ePID)
212878663

Product Key Features

Author
D.T. Hart
Publication Name
Leishmaniasis: The Current Status and New Strategies for Control: Proceedings of the NATO Advanced Study Institute, Zakynthos (Greece), 1987
Format
Paperback
Language
English
Subject
Medicine, Biology
Publication Year
2013
Type
Textbook
Number of Pages
1041 Pages

Dimensions

Item Height
254mm
Item Width
178mm
Volume
171
Item Weight
1974g

Additional Product Features

Series Title
Nato Science Series a
Country/Region of Manufacture
United States
Editor
D.T. Hart

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BOOKS ETC LIMITED
Andy Smith
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