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In Vitro Neurotoxicolog y: Principles and Challenges by Evelyn Tiffany-Castig lion
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Item specifics
- Condition
- ISBN-13
- 9781588290472
- Book Title
- In Vitro Neurotoxicology
- ISBN
- 9781588290472
- Subject Area
- Medical
- Publication Name
- In Vitro Neurotoxicology : Principles and Challenges
- Item Length
- 9.3 in
- Publisher
- Humana Press
- Subject
- Toxicology, Pharmacology
- Publication Year
- 2003
- Series
- Methods in Pharmacology and Toxicology Ser.
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Item Width
- 6.1 in
- Item Weight
- 26.5 Oz
- Number of Pages
- Xv, 331 Pages
About this product
Product Information
Neurotoxicity assessment with in vitro systems is the focus of both increasing expectations and heightened challenges. The purpose of this book is to synthesize principles and concepts of in vitro neurotoxicology that will facilitate the development of significantly improved methods and systems for in vitro neurotoxicity testing, with emphasis on their relevance to in vivo systems. Respected leaders in the field and new investigators who are exploring emerging frontiers in the area of genomic toxicology have assembled chapters that are arranged around major themes or central ideas, rather than around individual toxicants or specific in vitro models. Emphasis is given to several neurotoxicants that are of prominent human health concern and about which metabolism and dose-responses are best understood, both in vivo and in vitro: lead, mercury, organophosphorus insecticides, polychlorinated biphenyls and dioxin, ethanol, and endogenous proteins. In addition, this book provides an Appendix containing a critically reviewed list of related, major works, reviews, and seminal work related to in vitro neurotoxicology that have appeared in the past ten years.
Product Identifiers
Publisher
Humana Press
ISBN-10
1588290476
ISBN-13
9781588290472
eBay Product ID (ePID)
2399599
Product Key Features
Publication Name
In Vitro Neurotoxicology : Principles and Challenges
Format
Hardcover
Language
English
Subject
Toxicology, Pharmacology
Publication Year
2003
Series
Methods in Pharmacology and Toxicology Ser.
Type
Textbook
Subject Area
Medical
Number of Pages
Xv, 331 Pages
Dimensions
Item Length
9.3 in
Item Width
6.1 in
Item Weight
26.5 Oz
Additional Product Features
LCCN
2003-049933
Intended Audience
Scholarly & Professional
Number of Volumes
1 Vol.
Lc Classification Number
Rm300-666
Reviews
"This book covers a wide range of topics, starting with a nice overview of the field of neurotoxicology. Moving on to the meat of the material, the effects of toxins on neural development, function, and degeneration are examined, using well studied neurotoxicants as examples. A thorough list of articles as well as an annotated reading list are valuable additions, making the book an excellent reference. This is a valuable reference for anyone studying the advances in neurotoxicology. It is concise and easy to comprehend, without sacrificing quality in the process. It is written by leaders in the field, ensuring the information is relevant and up-to-date."-Doody's Health Sciences Book Review Journal "This is a useful book that updates new an improved in vitro methods to help further understanding neurotoxicology. The information presented is exciting, the methods proposed are often innovative, and readers will find a challenging glimpse into the future contributions their own research efforts can generate. Neurotoxicologists will find studying this volume rewarding and inspiring." - Vet Human Toxicol "...a helpful and up to date book..." - BTS Newsletter, "This book covers a wide range of topics, starting with a nice overview of the field of neurotoxicology. Moving on to the meat of the material, the effects of toxins on neural development, function, and degeneration are examined, using well studied neurotoxicants as examples. A thorough list of articles as well as an annotated reading list are valuable additions, making the book an excellent reference. This is a valuable reference for anyone studying the advances in neurotoxicology. It is concise and easy to comprehend, without sacrificing quality in the process. It is written by leaders in the field, ensuring the information is relevant and up-to-date."-Doody's Health Sciences Book Review Journal"This is a useful book that updates new an improved in vitro methods to help further understanding neurotoxicology. The information presented is exciting, the methods proposed are often innovative, and readers will find a challenging glimpse into the future contributions their own research efforts can generate. Neurotoxicologists will find studying this volume rewarding and inspiring." - Vet Human Toxicol"...a helpful and up to date book..." - BTS Newsletter
Table of Content
In Vitro Neurotoxicology.- Predictive Value of In Vitro Systems for Neurotoxicity Risk Assessment.- Exposure-Dose-Response Paradigm as It Relates to Toxicogenomics.- In Vitro Studies of Neurotoxicant Effects on Cellular Homeostasis.- Role of Apoptosis in Neurotoxicology.- Impairment of Neurotransmitter Metabolism and Function by Neurotoxicants.- Cell-Type Specific Responses of the Nervous System to Lead.- Effects of Toxicants on Neural Differentiation.- Impairment of Synaptic Function by Exposure to Lead.- Aggregating Brain Cell Cultures for Neurotoxicological Studies.- Use of Complimentary In Vitro and In Vivo Methods for Assessing Neuroendocrine Disruptors.- Establishing In Vitro Models to Study Endogenous Neurotoxicants.
Copyright Date
2004
Illustrated
Yes
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