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Estrogen Receptor and Breast Cancer: Celebrating the 60th Anniversary of the Dis
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- Buy it nowEstrogen Receptor and Breast Cancer: Celebrating the 60th Anniversary of the Dis
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Located in: Ohio, United States
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eBay item number:364903822987
Item specifics
- Condition
- ISBN-13
- 9783030075934
- Book Title
- Estrogen Receptor and Breast Cancer
- ISBN
- 9783030075934
- Publication Year
- 2018
- Type
- Textbook
- Format
- Paperback
- Language
- English
- Publication Name
- Estrogen Receptor and Breast Cancer: Celebrating the 60th Anniversary of the Discovery of Er
- Item Height
- 235mm
- Publisher
- Springer Nature Switzerland A&G
- Item Width
- 155mm
- Subject
- Medicine, Biology
- Item Weight
- 658g
- Number of Pages
- 417 Pages
About this product
Product Information
The discovery of ER by Dr. Elwood Jensen exactly 60 years ago has not only led to the birth of a whole new vital nuclear receptor research field but also made a rapid, direct and lasting impact on the treatment and prevention of breast cancer. Since that landmark discovery, tremendous progress has been made in our understanding of the molecular functions of ER and development of targeted therapies against ER pathways for breast cancer treatment. However, there is currently no book available addressing these discoveries and recent advancement in a historical and systematic fashion. This book is intended to provide comprehensive, most up-to-date information on the history and recent advancement of ER and breast cancer by world renowned leaders in the field. These chapters include the history of the discovery of ER; physiological and pathological roles of ER; recent discovery of ER cistrome, transcriptome and its regulation of noncoding RNAs such as microRNAs and enhancer RNAs in breast cancer; development and clinical practices of the first targeted therapy Tamoxifen and other antiestrogens for breast cancer treatment; structural basis of ER and antiestrogen actions; molecular insights into endocrine resistance; the role of ER mutants, ER-beta and environmental estrogens in breast cancer; and emerging state-of-the-art therapeutic approaches currently in development to overcome treatment resistance and future perspectives. The book will provide undergraduate and graduate students, basic scientists and clinical cancer researchers, residents, fellows, as well as clinicians, oncology educators and the general public a thorough and authoritative review of these exciting topics.
Product Identifiers
Publisher
Springer Nature Switzerland A&G
ISBN-13
9783030075934
eBay Product ID (ePID)
28046580950
Product Key Features
Publication Name
Estrogen Receptor and Breast Cancer: Celebrating the 60th Anniversary of the Discovery of Er
Format
Paperback
Language
English
Subject
Medicine, Biology
Publication Year
2018
Type
Textbook
Number of Pages
417 Pages
Dimensions
Item Height
235mm
Item Width
155mm
Item Weight
658g
Additional Product Features
Series Title
Cancer Drug Discovery and Development
Country/Region of Manufacture
Switzerland
Editor
Xiaoting Zhang
Item description from the seller
Business seller information
ABC Books Ltd
Unit 2D
Gatwick Gate Industrial Estate
Crawley, Lowfield Heath
London
RH11 0TG
United Kingdom
Value added tax number:
- GB 324767388
Trade registration number:
- 05034144
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CRN Number:
- 05034144
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eBay item number:364903822987
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