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Molecular Mechanisms of Dementia by Wilma Wasco (English) Hardcover Book
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- Buy it nowMolecular Mechanisms of Dementia by Wilma Wasco (English) Hardcover Book
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eBay item number:395159246113
Item specifics
- Condition
- ISBN-13
- 9780896033719
- Book Title
- Molecular Mechanisms of Dementia
- ISBN
- 9780896033719
- Subject Area
- Medical
- Publication Name
- Molecular Mechanisms of Dementia
- Item Length
- 10 in
- Publisher
- Humana Press
- Subject
- Neurology
- Publication Year
- 1996
- Series
- Contemporary Neuroscience Ser.
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Item Width
- 7 in
- Item Weight
- 31.4 Oz
- Number of Pages
- Xi, 312 Pages
About this product
Product Information
Wilma Wasco and Rudolph Tanzi bring together the best and latest thinking by leading scientists on the etiologic and pathogenic events responsible for the onset of Alzheimer's disease and related dementias. In presenting the various mechanisms and multifaceted approaches currently being employed, the distinguished contributors review such critical factors as apoptosis, energy metabolism, excitotoxicity and calcium-mediated cell death, free radicals, electrophysiological abnormalities, environmental toxins, degeneration of neural networks, and modification of the cytoskeleton. They also examine mechanisms by which ischemia and hypoxia result in dementia. The book provides critical insights into the necessary direction of future investigations of dementia.
Product Identifiers
Publisher
Humana Press
ISBN-10
0896033716
ISBN-13
9780896033719
eBay Product ID (ePID)
513162
Product Key Features
Publication Name
Molecular Mechanisms of Dementia
Format
Hardcover
Language
English
Subject
Neurology
Publication Year
1996
Series
Contemporary Neuroscience Ser.
Type
Textbook
Subject Area
Medical
Number of Pages
Xi, 312 Pages
Dimensions
Item Length
10 in
Item Width
7 in
Item Weight
31.4 Oz
Additional Product Features
LCCN
96-038858
Intended Audience
Scholarly & Professional
Number of Volumes
1 Vol.
Lc Classification Number
Rc346-429.2
Reviews
In conclusion, the first chapters of this book provide a lot of very recent information related to the production and the toxicity of the amyloid peptide as well as to the possible role of new genes involved in Alzheimer's disease. It represents a very interesting review for scientists studying the cellular and molecular mechanisms involved in the neurodegeneration of Alzheimer's disease.-ACTA Neurologica Belgica "The text is logically organized, which helps in making a transition from one subject to the other. The topics are well selected; classical, and new, often controversial, research is covered. Each chapter is succinct and ends with an informative summary...this expertly written overview also provides directions for future studies...a valuable reference and source of inspiration. It is highly recommended to all interested in the molecular basis of neurodegenerative diseases."-Cell Biology International, In conclusion, the first chapters of this book provide a lot of very recent information related to the production and the toxicity of the amyloid peptide as well as to the possible role of new genes involved in Alzheimer's disease. It represents a very interesting review for scientists studying the cellular and molecular mechanisms involved in the neurodegeneration of Alzheimer's disease.-ACTA Neurologica Belgica"The text is logically organized, which helps in making a transition from one subject to the other. The topics are well selected; classical, and new, often controversial, research is covered. Each chapter is succinct and ends with an informative summary...this expertly written overview also provides directions for future studies...a valuable reference and source of inspiration. It is highly recommended to all interested in the molecular basis of neurodegenerative diseases."-Cell Biology International
Table of Content
1 Etiological Clues from Gene Defects Causing Early Onset Familial Alzheimer's Disease.- 2 Potential Biological Mechanisms of ApoE in Alzheimer's Disease.- 3 Understanding the Biology and Molecular Pathogensis of Alzheimer's Disease in Transgenic Mice Expressing Amyloid Precursor Proteins.- 4 Mechanism for ?-Amyloid Overproduction in Alzheimer Disease: Possible Antisense RNA-Mediated Generation of a 5?-Truncated?APP mRNA Encoding 12-kDa C-Terminal Fragment of ?APP, the Immediate Precursor of A?.- 5 Apoptosis and Alzheimer's Disease.- 6 The ?-Amyloid Model of Alzheimer's Disease: Conformation Change, Receptor Cross-Linking, and the Initiation of Apoptosis.- 7 Energy/Glucose Metabolism in Neurodegenerative Diseases.- 8 Calcium Homeostasis and Free Radical Metabolism as Convergence Points in the Pathophysiology of Dementia.- 9 ?-Amyloid-Derived Free Radical Oxidation: A Fundamental Process in Alzheimer's Disease.- 10 Inflammatory Pathways: Implications in Alzheimer's Disease.- 11 Inflammatory Mediators in Alzheimer's Disease.- 12 ? Protein and the Neurofibrillary Pathology of Alzheimer's Disease.- 13 Anatomy of Pathological Alterations in Alzheimer's Disease.- 14 Cerebral Zinc Metabolism in Alzheimer's Disease.- 15 Potassium Channels and Calcium Release: Pat ho physiological and Diagnostic Implications for Alzheimer's Disease.- 16 Pick Disease.- 17 Ischemia.- 18 Prion Diseases and Dementia.
Copyright Date
1997
Dewey Decimal
616.8/3
Dewey Edition
20
Illustrated
Yes
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eBay item number:395159246113
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