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Voltage-gated Sodium Channels: Structure, Function and Channelopathie
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- Buy it nowVoltage-gated Sodium Channels: Structure, Function and Channelopathies by Mohame
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Item specifics
- Condition
- ISBN-13
- 9783030079826
- Book Title
- Voltage-gated Sodium Channels: Structure, Function and Channelopa
- ISBN
- 9783030079826
- Subject Area
- Science, Medical
- Publication Name
- Voltage-Gated Sodium Channels : Structure, Function and Channelopathies
- Publisher
- Springer International Publishing A&G
- Item Length
- 9.2 in
- Subject
- Genetics, Life Sciences / Human Anatomy & Physiology, Pharmacology, Chemistry / General
- Publication Year
- 2019
- Series
- Handbook of Experimental Pharmacology Ser.
- Type
- Textbook
- Format
- Trade Paperback
- Language
- English
- Item Height
- 0.9 in
- Item Weight
- 24.7 Oz
- Item Width
- 6.1 in
- Number of Pages
- X, 450 Pages
About this product
Product Information
This book provides a timely state-of-the-art overview of voltage-gated sodium channels, their structure-function, their pharmacology and related diseases. Among the topics discussed are the structural basis of Na+ channel function, methodological advances in the study of Na+ channels, their pathophysiology and drugs and toxins interactions with these channels and their associated channelopathies.
Product Identifiers
Publisher
Springer International Publishing A&G
ISBN-10
3030079821
ISBN-13
9783030079826
eBay Product ID (ePID)
13038535210
Product Key Features
Number of Pages
X, 450 Pages
Language
English
Publication Name
Voltage-Gated Sodium Channels : Structure, Function and Channelopathies
Publication Year
2019
Subject
Genetics, Life Sciences / Human Anatomy & Physiology, Pharmacology, Chemistry / General
Type
Textbook
Subject Area
Science, Medical
Series
Handbook of Experimental Pharmacology Ser.
Format
Trade Paperback
Dimensions
Item Height
0.9 in
Item Weight
24.7 Oz
Item Length
9.2 in
Item Width
6.1 in
Additional Product Features
Intended Audience
Trade
Series Volume Number
246
Number of Volumes
1 Vol.
Illustrated
Yes
Lc Classification Number
Rm300-666
Table of Content
Preface.- Part I.- Evolution of voltage-gated sodium channels.- 1. Evolutionary History of Voltage-Gated Sodium Channels.- 2. Mining Protein Evolution for Insights into Mechanisms of Voltage-Dependent Sodium Channel Auxiliary Subunits. - Part II. The structural basis of sodium channel function.- 3. Structural and Functional Analysis of Sodium Channels Viewed from an Evolutionary Perspective.- 4. The Cardiac Sodium Channel and Its Protein Partners.- 5. : Posttranslational Modification of Sodium Channels.- 6. Sodium Channel Trafficking.- 7. pH Modulation of Voltage-Gated Sodium Channels.- 8. Regulation of Cardiac Voltage-Gated Sodium Channel by Kinases: Roles of Protein Kinases A and C.- Part III. Drugs and toxins interactions with sodium channels.- 9. Toxins That Affect Voltage-Gated Sodium Channels.- 10. Mechanisms of Drug Binding to Voltage-Gated Sodium Channels.- 11. Effects of Benzothiazolamines on Voltage-Gated Sodium Channels.- 12. Structural Models of Ligand-Bound Sodium Channels.- 13. Selective Ligands and Drug Discovery Targeting the Voltage-Gated Sodium Channel Nav1.7.- Part IV. Pathophysiology of sodium channels.- 14. Sodium Channelopathies of Skeletal Muscle.- 15. Cardiac Arrhythmias Related to Sodium Channel Dysfunction.- 16. Translational Model Systems for Complex Sodium Channel Pathophysiology in Pain.- 17. Gating Pore Currents in Sodium Channels.- 18. Calculating the Consequences of Left-Shifted Nav Channel Activity in Sick Excitable Cells.- 19. Voltage-Gated Sodium Channel b Subunits and Their Related Diseases.
Copyright Date
2018
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